Publications
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2026#
Chandio, B. Q., Feng, Y., Gari, I. B., Alibrando, J. D., Thomopoulos, S. I., Villalón-Reina, J. E., Liou, K., Somu, S., Yoo, H., Nir, T. M., et al. (2026). “Tractometry-Based Quantification of Along-Tract White-Matter Hemispheric Asymmetry in Alzheimer’s Disease.” bioRxiv. Scholar
Nabulsi, L., Feng, Y., Chandio, B. Q., Villalon-Reina, J. E., Ba Gari, I., Alibrando, J. D., Nir, T. M., Juliano, A. C., Pancholi, D., Roundy, G. S., et al. (2026). “Along-Tract Microstructural Alterations Associated with Stimulant Misuse Localized using Diffusion MRI Tractometry.” bioRxiv. Scholar
2025#
Feng, Y., Chandio, B. Q., Villalon-Reina, J. E., Thomopoulos, S. I., Nir, T. M., Benavidez, S., Laltoo, E., Chattopadhyay, T., Joshi, H., Venkatasubramanian, G., et al. (2025). “Microstructural mapping of neural pathways in Alzheimer’s disease using macrostructure-informed normative tractometry.” Alzheimer’s & Dementia, 21(1), e14371. Scholar
Kim, G. S., Chandio, B. Q., Benavidez, S. M., Thompson, P. M., & Lawrence, K. E. (2025). “White matter microstructural alterations in autism localized with bundle analytics.” 2025 IEEE 22nd international symposium on biomedical imaging (ISBI), 1–5. Scholar
Shuai, Y., Chandio, B. Q., Feng, Y., Villalon-Reina, J. E., Nir, T. M., Ching, C. R., Gari, I. B., Thomopoulos, S. I., Alibrando, J. D., John, J. P., et al. (2025). “Deterministic versus probabilistic tractography: Impact on white matter bundle shape.” 2025 21st International Symposium on Biomedical Image Processing and Analysis (SIPAIM), 1–4. Scholar
Chandio, B. Q., Nir, T. M., Villalon-Reina, J. E., Thomopoulos, S. I., Feng, Y., Reid, R. I., Jack, C. R., Weiner, M. W., Garyfallidis, E., Jahanshad, N., et al. (2025). “White Matter Tract Vulnerability to Amyloid Pathology on the Alzheimer’s Disease Continuum.” 2025 21st International Symposium on Biomedical Image Processing and Analysis (SIPAIM), 1–5. Scholar
Feng, Y., Shuai, Y., Villalón-Reina, J. E., Chandio, B. Q., Thomopoulos, S. I., Nir, T. M., Jahanshad, N., & Thompson, P. M. (2025). “Streamline density normalization: A robust approach to mitigate bundle variability in multi-site diffusion mri.” International Workshop on Computational Diffusion MRI, 44–56. Scholar
Kim, G., Chandio, B., Benavidez, S., Thompson, P. M., & Lawrence, K. E. (2025). “Localized Mapping of White Matter Microstructural Alterations in Autism Using Advanced Tractometry.” INSAR 2025. Scholar
Chandio, B. Q., Schilling, K. G., & Villalón-Reina, J. E. (2025). “Methods and applications of diffusion MRI tractometry.” Frontiers in Neuroscience, 19, 1737026. Scholar
Chandio, B. Q., Villalón-Reina, J. E., Nir, T. M., Thomopoulos, S. I., Feng, Y., Benavidez, S., Jahanshad, N., Harezlak, J., Garyfallidis, E., & Thompson, P. M. (2025). “Amyloid, Tau, and APOE in Alzheimer’s Disease: Impact on White Matter Tracts.” Proceedings of the Pacific Symposium on Biocomputing, 30, 394–411. Scholar
Shuai, Y., Feng, Y., Villalon-Reina, J. E., Nir, T. M., Thomopoulos, S. I., Thompson, P. M., & Chandio, B. Q. (2025). “ASSESSING THE INFLUENCE OF TRACTOGRAPHY METHODS ON WHITE MATTER MICROSTRUCTURE AND TRACTOMETRY ANALYSIS IN ALZHEIMERS DISEASE.” bioRxiv, 2025–11. Scholar
Feng, Y., Villalón-Reina, J. E., Gari, I. B., Alibrando, J. D., Nir, T. M., Jahanshad, N., Chandio, B. Q., & Thompson, P. M. (2025). “Evaluating Sample-Size Efficiency and Sensitivity of Tractometry in Alzheimer’s Disease.” bioRxiv, 2025–11. Scholar
Kim, G. S., Chandio, B. Q., Benavidez, S. M., Feng, Y., Thompson, P. M., & Lawrence, K. E. (2025). “Mapping along-tract commissural and association white matter microstructural differences in autistic children and young adults.” Cerebral Cortex, 35(11), bhaf291. Scholar
Schilling, K. G., Villalon-Reina, J. E., & Chandio, B. Q. (2025). “Methods and Applications of Diffusion MRI Tractometry.” Frontiers Media SA. Scholar
Nabulsi, L., Chandio, B. Q., Kang, M. J., Im, Y., McPhilemy, G., Martyn, F. M., Roberts, G., Hallahan, B., Dannlowski, U., Borgers, T., et al. (2025). “Along-Tract Mapping of White Matter Microstructural Abnormalities in Bipolar Disorder using Diffusion MRI.” 2025 21st International Symposium on Biomedical Image Processing and Analysis (SIPAIM), 1–5. Scholar
2024#
Chandio, B. Q., Villalon-Reina, J. E., Nir, T. M., Thomopoulos, S. I., Feng, Y., Benavidez, S., Jahanshad, N., Harezlak, J., Garyfallidis, E., & Thompson, P. M. (2024). “Bundle analytics based data harmonization for multi-site diffusion mri tractometry.” 2024 46th annual international conference of the IEEE engineering in medicine and biology society (EMBC), 1–7. Scholar
Feng, Y., Chandio, B. Q., Villalon-Reina, J. E., Benavidez, S., Chattopadhyay, T., Chehrzadeh, S., Laltoo, E., Thomopoulos, S. I., Joshi, H., Venkatasubramanian, G., et al. (2024). “Deep normative tractometry for identifying joint white matter macro-and micro-structural abnormalities in Alzheimer’s disease.” 2024 46th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 1–7. Scholar
Chandio, B. Q., Reina, J. E. V., Nir, T. M., Thomopoulos, S. I., Feng, Y., Benavidez, S. M., Jahanshad, N., Harezlak, J., Garyfallidis, E., & Thompson, P. M. (2024). “Harmonized Tractometry Visualizes Alzheimer’s Disease Effects on the Brain’s White Matter Tract Microstructure.” Alzheimer’s & Dementia, 20, e089548. Scholar
Feng, Y., Villalón-Reina, J. E., Nir, T. M., Chandio, B. Q., Jahanshad, N., & Thompson, P. M. (2024). “BundleAGE: predicting white matter age using along-tract microstructural profiles from diffusion MRI.” 2024 20th International Symposium on Medical Information Processing and Analysis (SIPAIM), 1–4. Scholar
Newlin, N. R., Schilling, K., Koudoro, S., Chandio, B. Q., Kanakaraj, P., Moyer, D., Kelly, C. E., Genc, S., Chen, J., Yang, J. Y., et al. (2024). “MICCAI-CDMRI 2023 QuantConn challenge findings on achieving robust quantitative connectivity through harmonized preprocessing of diffusion MRI.” ArXiv, arXiv–2411. Scholar
Newlin, N., Schilling, K., Koudoro, S., Chandio, B. Q., Kanakaraj, P., Moyer, D., Kelly, C. E., Genc, S., Yang, J. Y., Wu, Y., et al. (2024). “Introducing QuantConn: Overcoming Challenging Diffusion Acquisitions with Harmonization.” International Workshop on Computational Diffusion MRI, 164–174. Scholar
2023#
Feng, Y., Chandio, B. Q., Chattopadhyay, T., Thomopoulos, S. I., Owens-Walton, C., Jahanshad, N., Garyfallidis, E., & Thompson, P. M. (2023). “Learning optimal white matter tract representations from tractography using a deep generative model for population analyses.” 18th International Symposium on Medical Information Processing and Analysis, 12567, 70–80. Scholar
Chandio, B. Q., Olivetti, E., Romero-Bascones, D., Harezlak, J., & Garyfallidis, E. (2023). “Bundlewarp, streamline-based nonlinear registration of white matter tracts.” bioRxiv. Scholar
Feng, Y., Chandio, B. Q., Thomopoulos, S. I., Chattopadhyay, T., & Thompson, P. M. (2023). “Variational autoencoders for generating synthetic tractography-based bundle templates in a low-data setting.” 2023 45th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC), 1–6. Scholar
Nabulsi, L., Chandio, B. Q., Dhinagar, N., Laltoo, E., McPhilemy, G., Martyn, F. M., Hallahan, B., McDonald, C., Thompson, P. M., & Cannon, D. M. (2023). “Along-tract statistical mapping of microstructural abnormalities in bipolar disorder: A pilot study.” 2023 45th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC), 1–7. Scholar
Feng, Y., Chandio, B. Q., Villalón-Reina, J. E., Thomopoulos, S. I., Joshi, H., Nair, G., Joshi, A. A., Venkatasubramanian, G., John, J. P., & Thompson, P. M. (2023). “BundleCleaner: unsupervised denoising and subsampling of diffusion MRI-derived tractography data.” International Workshop on Computational Diffusion MRI, 152–164. Scholar
Nabulsi, L., Chandio, B. Q., McPhilemy, G., Martyn, F. M., Roberts, G., Hallahan, B., Dannlowski, U., Kircher, T., Haarman, B., Mitchell, P., et al. (2023). “Multi-site statistical mapping of along-tract microstructural abnormalities in bipolar disorder with diffusion MRI Tractometry.” 2023 19th international symposium on medical information processing and analysis (SIPAIM), 1–5. Scholar
2022#
Chandio, B. Q., Chattopadhyay, T., Owens-Walton, C., Reina, J. E. V., Nabulsi, L., Thomopoulos, S. I., Garyfallidis, E., & Thompson, P. M. (2022). “Fiberneat: Unsupervised white matter tract filtering.” 2022 44th annual international conference of the IEEE engineering in medicine & biology society (EMBC), 5055–5061. Scholar
Yang, Q., Hansen, C. B., Cai, L. Y., Rheault, F., Lee, H. H., Bao, S., Chandio, B. Q., Williams, O., Resnick, S. M., Garyfallidis, E., et al. (2022). “Learning white matter subject-specific segmentation from structural MRI.” Medical physics, 49(4), 2502–2513. Scholar
Feng, Y., Chandio, B. Q., Chattopadhyay, T., Thomopoulos, S. I., Owens-Walton, C., Garyfallidis, E., Jahanshad, N., & Thompson, P. M. (2022). “Learning Streamline Embeddings with Variational Autoencoder for Intersubject Bundle Comparison in Alzheimer’s Disease.” Alzheimer’s & Dementia, 18, e066204. Scholar
Chandio, B. Q., Owens-Walton, C., Villalon-Reina, J. E., Nabulsi, L., Thomopoulos, S. I., Guaje, J., Garyfallidis, E., & Thompson, P. M. (2022). “Microstructural changes in the white matter tracts of the brain due to mild cognitive impairment.” Alzheimer’s & Dementia, 18, e065339. Scholar
Feng, Y., Chandio, B. Q., Chattopadhyay, T., Thomopoulos, S. I., Owens-Walton, C., Jahanshad, N., Garyfallidis, E., & Thompson, P. M. (2022). “Deep generative model for learning tractography streamline embeddings based on convolutional variational autoencoder.” International Society for Magnetic Resonance Imaging (ISMRM). Scholar
Romero-Bascones, D., Ayala, U., Barrenechea, M., Chandio, B. Q., Fadnavis, S., Park, J. S., Koudoro, S., & Garyfallidis, E. (2022). “Bundleatlasing: unbiased population-specific atlasing of bundles in streamline space.” Proceedings of the Annual Meeting of the International Society for Magnetic Resonance in Medicine. Scholar
Chandio, B. Q. (2022). “Advancing white matter tractometry of the brain using diffusion MRI and machine learning.” Indiana University. Scholar
2021#
Hansen, C. B., Yang, Q., Lyu, I., Rheault, F., Kerley, C., Chandio, B. Q., Fadnavis, S., Williams, O., Shafer, A. T., Resnick, S. M., et al. (2021). “Pandora: 4-D white matter bundle population-based atlases derived from diffusion MRI fiber tractography.” Neuroinformatics, 19(3), 447–460. Scholar
Schilling, K. G., Rheault, F., Petit, L., Hansen, C. B., Nath, V., Yeh, F., Girard, G., Barakovic, M., Rafael-Patino, J., Yu, T., et al. (2021). “Tractography dissection variability: What happens when 42 groups dissect 14 white matter bundles on the same dataset?” NeuroImage, 243, 118502. Scholar
Kruper, J., Yeatman, J. D., Richie-Halford, A., Bloom, D., Grotheer, M., Caffarra, S., Kiar, G., Karipidis, I. I., Roy, E., Chandio, B. Q., et al. (2021). “Evaluating the reliability of human brain white matter tractometry.” Aperture neuro, 1(1), 10–52294. Scholar
Gau, R., Noble, S., Heuer, K., Bottenhorn, K. L., Bilgin, I. P., Yang, Y., Huntenburg, J. M., Bayer, J. M., Bethlehem, R. A., Rhoads, S. A., et al. (2021). “Brainhack: Developing a culture of open, inclusive, community-driven neuroscience.” Neuron, 109(11), 1769–1775. Scholar
2020#
Chandio, B. Q., Risacher, S. L., Pestilli, F., Bullock, D., Yeh, F., Koudoro, S., Rokem, A., Harezlak, J., & Garyfallidis, E. (2020). “Bundle analytics, a computational framework for investigating the shapes and profiles of brain pathways across populations.” Scientific reports, 10(1), 17149. Scholar
Chandio, B. Q., & Garyfallidis, E. (2020). “StND: Streamline-based Non-rigid partial-Deformation Tractography Registration.” Medical imaging meets NeurIPS. Scholar
Preprints & Other Publications#
Garyfallidis, E., Côté, M., Chandio, B. Q., Fadnavis, S., Guaje, J., Aggarwal, R., St-Onge, E., Juneja, K. S., Koudoro, S., & Reagan, D. “DIPY Horizon: fast, modular, unified and adaptive visualization.” Scholar
Chandio, B. Q., & Garyfallidis, E. “StND: Non-Rigid Partial Deformation Tractography Registration.” Scholar
Chandio, B. Q., Chattopadhyay, T., Owens-Walton, C., Reina, J. E. V., Nabulsi, L., Thomopoulos, S. I., Guaje, J., Garyfallidis, E., & Thompson, P. M. “Visualizing 4,230 White Matter Tracts at Once.” Scholar
Hansen, C., Yang, Q., Rheault, F., Qamar, B., Williams, O., Resnick, S., Garyfallidis, E., Anderson, A. W., Descoteaux, M., Landman, B. A., et al. “Learning white matter fingerprints from structural information.” Scholar
Yang, Q., Hansen, C., Rheault, F., Qamar, B., Williams, O., Resnick, S., Garyfallidis, E., Anderson, A. W., Descoteaux, M., Landman, B. A., et al. “Mapping white matter specificity captured by diffusion tractography through deep learning on structural MRI.” Scholar
Chandio, B. Q., Thomopoulos, S. I., Thompson, P. M., Harezlak, J., & Garyfallidis, E. “BUAN 2.0, streamlines as functions, nonlinear registration, and subdivision of bundles for advanced tractometry.” Scholar